2023 (4 Publications)

Z. Liang, T. Liu, Q. Li, G. Zhang, B. Zhang, X. Du, J. Liu, Z. Chen, H. Ding, G. Hu, H. Lin, F. Zhu, C. Luo, Deciphering the functional landscape of phosphosites with deep neural network. Cell Reports 42, 113048 (2023) (SCI 大类一区)

F. Zhu, L. Deng, Y. Dai, G. Zhang, F. Meng, C. Luo, G. Hu, Z. Liang, PPICT: an integrated deep neural network for predicting inter-protein PTM cross-talk. Briefings in Bioinformatics 24, (2023) (SCI 大类二区)

Z. Zhou, Y. Lu, Z. Gu, Q. Sun, W. Fang, W. Yan, X. Ku, Z. Liang, G. Hu, HNRNPA2B1 as a potential therapeutic target for thymic epithelial tumor recurrence: An integrative network analysis. Computers in Biology and Medicine 155, 106665 (2023) (SCI 大类二区，并列通讯作者)

H. Jiang, S. Zu, Y. Lu, Z. Sun, A. Adeerjiang, Q. Guo, H. Zhang, C. Dong, Q. Wu, H. Ding, D. Du, M. Wang, C. Liu, Y. Tang, Z. Liang, C. Luo, A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region. Journal of Structural Biology, 107942 (2023) (SCI 大类三区，并列通讯作者)

2022 (2 Publications)

F. Zhu, S. Yang, F. Meng, Y. Zheng, X. Ku, C. Luo, G. Hu, Z. Liang, Leveraging Protein Dynamics to Identify Functional Phosphorylation Sites using Deep Learning Models. Journal of Chemical Information and Modeling 62, 3331-3345 (2022) (SCI 大类二区)

F. Zhu, F. Li, L. Deng, F. Meng, Z. Liang, Protein Interaction Network Reconstruction with a Structural Gated Attention Deep Model by Incorporating Network Structure Information. Journal of Chemical Information and Modeling 62, 258-273 (2022) (SCI 大类二区)

2021 (4 Publications)

Y. Zhu, F. Ye, Z. Zhou, W. Liu, Z. Liang, G. Hu, Insights into Conformational Dynamics and Allostery in DNMT1-H3Ub/USP7 Interactions. Molecules 26, (2021) (SCI 大类二区,并列通讯作者)

H. Zhang, J. He, G. Hu, F. Zhu, H. Jiang, J. Gao, H. Zhou, H. Lin, Y. Wang, K. Chen, F. Meng, M. Hao, K. Zhao, C. Luo, Z. Liang, Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family. Journal of Medicinal Chemistry 64, 15111-15125 (2021) (SCI 大类一区)

F. Meng, Z. Liang, K. Zhao, C. Luo, Drug design targeting active posttranslational modification protein isoforms. Medicinal Research Reviews 41, 1701-1750 (2021) (SCI 大类一区，并列一作)

Z. Liang, Y. Zhu, J. Long, F. Ye, G. Hu, Both intra and inter-domain interactions define the intrinsic dynamics and allosteric mechanism in DNMT1s. Computational and Structural Biotechnology Journal 41, 1701–1750 (2021) (SCI 大类二区)

2020 (2 Publications)

Z. Liang, Y. Zhu, X. Liu, G. Hu, Role of protein-protein interactions in allosteric drug design for DNA methyltransferases. Adv Protein Chem Struct Biol 121, (2020)

Z. Liang, G. M. Verkhivker, G. Hu, Integration of network models and evolutionary analysis into high-throughput modeling of protein dynamics and allosteric regulation: theory, tools and applications. Briefings in Bioinformatics 21, 815-835 (2020) (SCI 大类一区)

2018 (2 Publications)

W. Yan, D. Zhang, C. Shen, Z. Liang, G. Hu, Recent Advances on the Network Models in Target-based Drug Discovery. Current Topics in Medicinal Chemistry 18, 1031-1043 (2018) (SCI 大类三区，并列通讯作者)

Z. Liang, J. Hu, W. Yan, H. Jiang, G. Hu, C. Luo, Deciphering the role of dimer interface in intrinsic dynamics and allosteric pathways underlying the functional transformation of DNMT3A. Biochimica et Biophysica Acta. General Subjects 1862, 1667-1679 (2018) (SCI 大类二区)

2016 (1 Publication)

P. Xu, G. Hu, C. Luo, Z. Liang, DNA methyltransferase inhibitors: an updated patent review (2012-2015). Expert Opinion on Therapeutic Patents 26, 1017-1030 (2016) (SCI 大类二区)

2015 (4 Publications)

R. Zhou, Y. Xie, H. Hu, G. Hu, V. S. Patel, J. Zhang, K. Yu, Y. Huang, H. Jiang, Z. Liang, Y. G. Zheng, C. Luo, Molecular Mechanism underlying PRMT1 Dimerization for SAM Binding and Methylase Activity. Journal of Chemical Information and Modeling 55, 2623-2632 (2015) (SCI 大类二区，并列通讯作者)

J. Lu, H. Zeng, Z. Liang, L. Chen, L. Zhang, H. Zhang, H. Liu, H. Jiang, B. Shen, M. Huang, M. Geng, S. Spiegel, C. Luo, Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets. Scientific Reports 5, 14739 (2015) (SCI 大类二区，并列一作)

Z. Liang, G. Hu, Protein Structure Network-based Drug Design. Mini-Rev Med Chem 16, 1330-1343 (2015)(SCI 大类三区)

Z. Jiang, Z. Liang, B. Shen, G. Hu, Computational Analysis of the Binding Specificities of PH Domains.BioMed Research International 2015, 792904 (2015)(SCI 大类三区，并列一作)

2014 (2 Publications)

K. Zhu, X. Kong, D. Zhao, Z. Liang, C. Luo, c-MET kinase inhibitors: a patent review (2011 - 2013). Expert Opinion on Therapeutic Patents 24, 217-230 (2014) (SCI 大类二区，并列通讯作者)

Y. Xie, R. Zhou, F. Lian, Y. Liu, L. Chen, Z. Shi, N. Zhang, M. Zheng, B. Shen, H. Jiang, Z. Liang, C. Luo, Virtual screening and biological evaluation of novel small molecular inhibitors against protein arginine methyltransferase 1 (PRMT1). Organic & Biomolecular Chemistry 12, 9665-9673 (2014) (SCI 大类二区，并列通讯作者)

2013 and before (6 Publications)

Z. Liang, J. Ai, X. Ding, X. Peng, D. Zhang, R. Zhang, Y. Wang, F. Liu, M. Zheng, H. Jiang, H. Liu, M. Geng, C. Luo, Anthraquinone Derivatives as Potent Inhibitors of c-Met Kinase and the Extracellular Signaling Pathway. ACS Medicinal Chemistry Letters 4, 408-413 (2013)

Z. Liang, L. Zhang, L. Li, J. Liu, H. Li, L. Chen, K. Cheng, M. Zheng, X. Wen, P. Zhang, J. Hao, Y. Gong, X. Zhang, X. Zhu, J. Chen, H. Liu, H. Jiang, C. Luo, H. Sun, Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies. Eur J Med Chem 46, (2011)

Z. Liang, D. Zhang, J. Ai, L. Chen, H. Wang, X. Kong, M. Zheng, H. Liu, C. Luo, M. Geng, H. Jiang, K. Chen, Identification and synthesis of N'-(2-oxoindolin-3-ylidene)hydrazide derivatives against c-Met kinase. Bioorg Med Chem Lett 21, 3749-3754 (2011)

Z. Liang, L. Li, Y. Wang, L. Chen, X. Kong, Y. Hong, L. Lan, M. Zheng, C. Guang-Yang, H. Liu, X. Shen, C. Luo, K. K. Li, K. Chen, H. Jiang, Molecular basis of NDM-1, a new antibiotic resistance determinant. PLoS One(2011)

Z. Liang, X. Ding, J. Ai, X. Kong, L. Chen, C. Luo, M. Geng, H. Liu, K. Chen, H. Jiang, Discovering potent inhibitors against c-Met kinase: molecular design, organic synthesis and bioassay. Organic & Biomolecular Chemistry,  (2011)

Z. Liang, T. Shi, S. Ouyang, H. Li, K. Yu, W. Zhu, C. Luo, H. Jiang, Investigation of the catalytic mechanism of Sir2 enzyme with QM/MM approach: SN1 vs SN2? J Phys Chem B 114, 11927-11933 (2010)